Dose–response in structure–activity analysis
A classical Emax-type curve: fractional effect E = Emax·[D]/(EC₅₀ + [D]). Slide EC₅₀ to see how small structural changes that shift potency move the whole curve.
A classical Emax-type curve: fractional effect E = Emax·[D]/(EC₅₀ + [D]). Slide EC₅₀ to see how small structural changes that shift potency move the whole curve.