Photo credit: Holger Motzkau — Wikimedia Commons · CC BY-SA 3.0
Paul Modrich
born 1946 · United States · Contemporary
Nobel Chemistry 2015
American biochemist who deciphered how cells repair mismatched DNA bases after replication.
Nobel Prize work
He elucidated the mechanism of DNA mismatch repair, identifying and reconstituting the proteins — MutS, MutL, MutH and others — that detect and correct copying errors, showing how cells keep mutation rates low.