Photo credit: BloodIce — File:Ei-ichi Negishi.jpg (Wikimedia Commons) · CC BY-SA 4.0
Ei-ichi Negishi
1935–2021 · Japan, United States · 20th century
Nobel Chemistry 2010
Japanese-American chemist who developed organozinc-based palladium cross-coupling, a workhorse reaction for building carbon-carbon bonds.
Nobel Prize work
Fields
Related topics
Metal–carbon compounds
Organometallic compounds place a metal in direct contact with carbon. Their bonds range from highly polar M–C σ bonds to multicentre metal–ligand interactions such as η² alkene, η⁵ cyclopentadienyl and metal carbonyl coordination.
Homogeneous catalysis (Ziegler–Natta, Grubbs)
A homogeneous catalyst moves through a closed sequence of elementary steps in the same phase as the substrate. Small changes in ligands, oxidation state or vacant sites can redirect an entire cycle and change selectivity.